What is the purpose of the anti-drip design of deep well plates
Posted by Admin | 20 Nov
aim of design:
The anti-drip design of the deep well plate is designed to prevent liquids from dripping between deep wells to avoid cross-contamination and ensure the accuracy and reliability of experiments. This design feature is particularly important in high-throughput experiments, where frequent liquid handling and sampling can lead to sample-to-sample interference.
Spacing and well shape:
The first consideration in drip-proof design is the spacing between deep wells and the shape of the deep wells. Reasonable deep well design and layout can reduce the probability of liquid dripping on the plate. Generally, the spacing between deep wells should not be too small to ensure that they do not interfere with each other during sampling or liquid handling.
The design of the bottom of a deep well is critical to drip-proof performance. In general, the bottom is usually tapered to facilitate the flow of liquid in deep wells and reduce the volume of residual liquid when recovering liquid. The tapered bottom design can reduce the risk of liquid dripping between deep wells and improve the efficiency of experimental operations.
The choice of materials in a drip-proof design is also a key factor. The material of the plate is usually selected with good surface tension and wettability to reduce the residence time of liquid on the upper surface of the deep well. This helps liquids flow more easily in deep wells and reduces the chance of droplets forming.
Some deep well plates may have special surface coatings, such as hydrophobic or oleophobic coatings, to improve drip resistance. These coatings can make it easier for liquids to slide across surfaces, reducing the chance of liquids getting trapped and dripping between deep wells.
Adaptability to experimental conditions:
The drip-proof design also needs to consider the adaptability under different experimental conditions. For example, under high or low temperature experimental conditions, the material and design of the plate need to be able to maintain stable performance and prevent the impact of temperature changes on the anti-drip effect.