What are the designs for the bottom shape of deep well plates

Tapered bottom design:

The bottom of deep well plates is usually designed to be tapered. This design helps distribute fluids more evenly in deep wells while reducing the volume of residual fluid when recovering fluids. The tapered bottom not only improves the fluidity of liquids within deep wells, but also reduces the risk of liquid dripping between deep wells during liquid handling and sampling. In addition, the tapered bottom makes it easier for liquids to be absorbed and discharged, improving the efficiency of experimental operations.

Flat bottom design:

While tapered bottoms work well in many applications, some deep well plates may have a flat bottom design. This design is suitable for situations where special experiments need to be performed on the bottom, such as high-throughput fluorescence detection, where the bottom needs to be kept flat to ensure accurate light signal detection. However, deep-well plates with flat-bottom designs may be relatively inferior to tapered bottoms in terms of liquid recovery and avoiding cross-contamination.

V-shaped bottom design:

The V-shaped bottom design is a relatively new design trend. This design helps the accumulation and flow of liquid by forming a V-shaped groove at the bottom of the deep well, thereby reducing the volume of residual liquid. The V-shaped bottom design may provide better liquid handling performance in some special applications, especially for experiments that require minimizing liquid carryover.

U-shaped bottom design:

Similar to the V-shaped bottom design, the U-shaped bottom design also provides better liquid accumulation and flow by forming a U-shaped groove at the bottom. The U-shaped bottom design can reduce the volume of residual liquid, facilitate liquid recovery and avoid cross-contamination.